Pfizer Migrates to SAP S/4HANA on IBM Power10

PPfizerSource: IBMSeptember 2025

Pfizer achieved a 93% database reduction and 20% cost avoidance by migrating their global SAP environment to S/4HANA on IBM Power10 infrastructure.

Impact

93%

Database reduction

73%

Ledger reduction

20%

Cost avoidance

21%

Faster go-live

5%

Order-to-cash improvement

10+ hours

Migration completed ahead of schedule

Challenge

Pfizer needed to migrate decades of complex SAP applications to SAP S/4HANA while managing a massive 75TB ECC 6.0 database with minimal downtime across 50,000 users globally.

Solution

Implemented hybrid cloud architecture using IBM Power10 infrastructure with SAP S/4HANA, reducing physical footprint to six systems running 500+ virtual machines via PowerVM.

Tools & Technologies

What Leaders Say

Our go live was truly amazing. The star was actually IBM Power10.

Scott Groth, ERP Platform Engineering & Emerging Technologies

IBM Consulting was instrumental in helping us plan for success.

Raj Hase, Senior Director, Digital Finance Solutions
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Full Story

Pfizer, one of the world's largest biopharmaceutical companies with 85,000+ employees across 130 countries, faced the challenge of migrating decades of complex SAP applications to SAP S/4HANA while managing a massive 75TB database with minimal downtime for 50,000 global users.

Using IBM Power10 servers and IBM Consulting, Pfizer implemented a hybrid cloud architecture that reduced their physical footprint to just six systems running 500+ virtual machines via PowerVM. The migration of 46TB of raw data was completed 10 hours ahead of the 54-hour window.

The results were transformative: a 93% database reduction, 73% ledger reduction, 20% cost avoidance for new projects, 21% faster go-live time, and a 5% improvement in the order-to-cash cycle. IBM Power Virtual Server now enables Pfizer to run the same architecture in the cloud.

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